AN354 pill contains Sildenafil, which is commonly used to treat erectile dysfunction (ED). When taken orally, it can take anywhere from 30 minutes to an hour for the effects to kick in. Once it has taken effect, the effects can last anywhere from 2 to 4 hours. However, it is important to note that the duration of the effects can vary from person to person, depending on factors such as age, weight, and overall health. You should take AN354 as directed by your healthcare provider and not exceed the recommended dosage. Speaking with your doctor about any potential side effects or interactions with other medications is important before taking AN354.